All products on this site are for In-Vitro Research, Development use only. Products are Not for Human consumption of any kind.

Humanin Peptide Benefits

Humanin Peptide BenefitsHumanin Peptide benefits include protecting against Alzheimer’s disease and dementia diseases. Studies to date, show Humanin can protect against cellular necrosis. It is the main cause of cells dying that can cause dementia. If you are in the dementia research community you can buy Humanin Peptide 10mg for $155.00. We supply premium research products for study only. All of our research products are US-made by Peptide Sciences.

What is Humanin?

Humanin 10mg is a research peptide and is still being tested.  A study conducted at UCLA has also discovered that Humanin plays a vital role in protecting neurons against oxidative stress, a key factor in damage caused by Alzheimer’s Disease.

CNS-derived cell line M1 mouse neurons were found to produce Humanin peptides. It then protects against oxygen/glucose deprivation and hydrogen peroxide-induced cell death. Humanin peptide is also capable of protecting against the loss of calcium homeostasis and of decreasing production of A beta, beta-secretase activity and amyloid precursor protein.

What does Humanin peptide do?

It has also been linked to neuroprotection by way of decreasing the production of neurotoxic NO, which damages the brain’s neuronal networks, and by decreasing A-beta plaque formation. Researchers have found that Humanin peptides can also protect neurons against toxicity.

Humanin Benefits

Humanin treatment has been found to increase choline acetyltransferase activity and to enhance brain-derived neurotrophic factor (BDNF). In terms of protection against Alzheimer’s disease, Humanin has been shown to reduce soluble A beta and phosphorylated tau in the brain. Humanin was also found to protect against neuronal damage caused by HIV Tat. Tat protein of human immunodeficiency virus (HIV) was found to be involved in neurodegenerative diseases such as Alzheimer’s disease, Huntington’s disease, and Parkinson’s disease.

Humanin Supplement Study

Humanin has been shown to have the ability to protect against cell death caused by Tat in the human neuroblastoma cell line, BE(2)-C cells. It has also been shown to prevent Tat-induced activation of the pro-apoptotic caspase-3. The Humanin derived from human neural stem cells (hNSCs) has also been found to be protective in an MPTP mouse model of Parkinson’s disease.

Humanin Peptide Review

From the website: “It is known that amyloid proteins interact to form oligomers and fibrils. Fibrils are the toxic component of amyloid plaques and other amyloid disorders. Humanin is the peptide with the smallest and most stable molecular weight that binds amyloid peptides in Alzheimer’s disease.

The peptide acts as a decoy to prevent the oligomerization of amyloid peptides and may also prevent amyloid fibril formation. The binding to amyloid peptides may interfere with normal amyloid precursor protein processing by inhibition of amyloid beta oligomerization.” It’s very early research but there seems to be a lot of potential for humanin being used to treat or prevent dementia. It may be possible to use something like humanin to target other neurodegenerative diseases.

Humanin Discovery

The name humanin was coined in 2001 by Peter C. Dooley, who was then working at the University of Alberta. He and his colleagues found that injection of small quantities of humanin into mice was sufficient to stimulate neuron regeneration and recovery from certain neurodegenerative conditions, such as a stroke. This led to the hypothesis that humanin was naturally produced in the brain, but no studies to support this have been published. The humanin gene was subsequently cloned by two research groups independently in 2003 and 2004.

Humanin Structure

Humanin is a peptide that has 28 amino acids. It is synthesized as a 117 amino acid preproprotein containing a 22 amino acid propeptide. Function Humanin has been shown to have cytoprotective properties and to act as a ligand of the Bax-Bcl-2 apoptotic protein signaling pathway. Humanin also functions as a neuroprotective factor and may prevent neurodegeneration.

Furthermore, humanin is able to bind Aβ1-42, a toxic amyloid peptide related to Alzheimer’s disease (AD). Humanin protects neurons from Aβ toxicity by antagonizing the interaction between Aβ and Bax. Humanin is expressed in the brain and it is possible that it is secreted into the circulation from the brain and/or that it is synthesized in the liver and secreted into the circulation.

The sequence of Humanin

Humanin can be found in the serum, plasma and in urine. It has also been found in the brain of adult mice, indicating that it is produced in the brain. Discovery in patients Humanin was first detected in patients with Alzheimer’s disease in 2003.

Role in dementia

Humanin is a brain derived peptide that is produced in the human brain. Humanin expression and secretion is altered in the presence of AD. Humanin is a ligand for the Bcl-2 anti-apoptotic protein and it prevents the apoptotic cell death of neurons in models of neurodegenerative diseases such as stroke and AD. Humanin levels are decreased in AD and in other neurodegenerative disorders including stroke, traumatic brain injury, and Parkinson’s disease.

Humanin was initially proposed as a potential treatment for Alzheimer’s disease but it is unclear how it would work to protect the brain. Some researchers claim that humanin can be used to treat AD. It has been shown that there is a correlation between the rate of dementia and the age of a person.

Humanin Results

In the case of a person who is very young when they develop dementia, there is a high possibility that their cause of dementia will be an infectious illness. On the other hand, an adult who is older when they develop dementia is more likely to develop Alzheimer’s disease or one of the other dementias. Potential as a treatment Humanin is a peptide, and a number of peptides are currently being developed as possible treatments for conditions that affect the nervous system including neurodegenerative disorders such as Alzheimer’s disease.

Humanin Peptide Benefits for Alzheimer’s Disease

Humanin may be a potential drug for the treatment of Alzheimer’s disease. Because of the potential beneficial effects of humanin on the brain, researchers are considering humanin as a treatment for a number of diseases.

Studies have been done in mice and rats to test the effect of humanin on the brain. These studies showed that humanin could protect neurons from Aβ toxicity by antagonizing the interaction between Aβ and Bax. This suggests that humanin may be used as a therapy for Alzheimer’s disease.

Humanin peptide supplement

Research has shown that humanin could be used to treat conditions of oxidative stress. Oxidative stress is a condition where there is a greater-than-normal amount of free radicals present in the body. Oxidative stress can be caused by any number of factors, including toxins, smoking, diet, exercise and inflammation.

Research has shown that humanin could be used to treat conditions of oxidative stress. Oxidative stress is a condition where there is a greater-than-normal amount of free radicals present in the body.

Oxidative stress can be caused by any number of factors, including toxins, smoking, diet, exercise and inflammation. Research shows that oxidative stress may be a result of mitochondrial dysfunction and/or dysfunction of enzymes and systems involved in the mitochondria.

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All products on this site are for In-Vitro Research, Development use only. Products are Not for Human consumption of any kind.